Question 1

What is epitalon and what is it used for?

Accepted Answer

Epitalon (also spelled epithalon, or AEDG) is a synthetic four-amino-acid peptide built from a pineal-gland extract. In research it is studied for aging, mainly for its effect on telomeres and the sleep-melatonin cycle. It is not FDA-approved and is sold for research use only.

Question 2

What does epitalon do?

Accepted Answer

In lab studies on human cells, epitalon raised telomerase activity and let cells divide more times than usual. In animals it has been linked to longer lifespan. The strongest human data come from the related pineal extract, not the synthetic peptide, and come from non-blinded studies, so the human picture is still limited.

Question 3

How is epitalon commonly dosed in research?

Accepted Answer

Reported protocols are short and spaced out. A common pattern is about 5 mg per day by subcutaneous injection for 20 days, or 10 mg per day for 10 days, repeated two to three times a year. This describes what has been reported in research and community sources, not a personal recommendation.

Question 4

How do you reconstitute epitalon?

Accepted Answer

A simple mix for a 10 mg vial is 2.0 mL of bacteriostatic water, which gives 5 mg/mL. On that mix, a 5 mg dose is 1.0 mL, or 100 units on a U-100 syringe. For a 50 mg vial, 5.0 mL of BAC water gives 10 mg/mL. Use the calculator for any other vial size.

Question 5

How do you reconstitute a 50 mg epitalon vial?

Accepted Answer

Adding 5.0 mL of bacteriostatic water to a 50 mg vial gives a 10 mg/mL concentration. On that mix, a 5 mg dose is 0.5 mL (50 units) and a 10 mg dose is 1.0 mL (100 units). Swirl gently, do not shake, and refrigerate after mixing.

Question 6

When should epitalon be taken, and where is it injected?

Accepted Answer

Most reported protocols use evening or bedtime dosing to line up with the natural melatonin rhythm. The common route is a subcutaneous injection into the fat under the skin, with sites like the abdomen or thigh rotated each day to avoid irritation.

Question 7

What is the half-life of epitalon?

Accepted Answer

Epitalon clears the bloodstream very quickly, on the order of minutes, which is typical for tiny peptides. Researchers think its effects last longer than its time in the blood because it may act on gene activity rather than staying in circulation. This is one reason short, repeated cycles are reported.

Question 8

What are the observed effects of epitalon?

Accepted Answer

Reported observed effects are usually mild and injection-related, like redness or soreness at the site, and sometimes mild drowsiness with evening dosing. The larger concern is the unknowns: long-term human safety data are limited, and people with a cancer history are flagged as cautious cases because of the telomerase question.

Question 9

Is epitalon FDA-approved?

Accepted Answer

No. As of June 2026, epitalon is not FDA-approved for any use and is not a dietary supplement. It is sold as a research-use-only chemical, which is not made or labeled for human use.

Question 10

Is this page medical advice?

Accepted Answer

No. This is an educational research reference. It reports dosing context, reconstitution math, and evidence, but it is not a treatment plan. Talk to a qualified clinician about any personal health decision.

Phase	Reference amount	Units / volume
Days 1–20 (Cycle On)	5,000 mcg (5 mg)	100 units (1.00 mL)
Weeks 4–26 (Cycle Off)	0 mcg	—

Epitalon (Epithalon).

Calculated-volume support unavailable

Cited protocol & reconstitution guide