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Glutathione

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Protocol01

Glutathione

Longevity

Vials · 500 / 1000 mg

01Protocol

Vials: 500 / 1000 mg
Dosing data: Lab reference — not listed

02Quick calculator

03Mechanism of action

Glutathione is a tripeptide (glutamate-cysteine-glycine) that serves as the main intracellular antioxidant and is involved in detoxification and immune function.

04Study endpoints

6-month RCT of oral glutathione: body stores rose 30–35% in red cells, plasma and lymphocytes and 260% in cheek cells in the higher arm; natural-killer cytotoxicity more than doubled at 3 months.
4-week RCT in 60 people: oral glutathione lowered melanin indices, significantly more than placebo at two of six skin sites.

05Safety & regulatory findings

Sold as a dietary supplement; injectable glutathione is not FDA-approved for skin lightening.
Both trials reported glutathione as well tolerated; long-term safety has not been established.

06Citations

2 references · view