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Start

2 mg

Range

2–5 mg per week

Frequency

2× weekly (loading), then weekly

Cycle

4–6 week loading, then maintenance

Vials

5 / 10 mg

Titration

1. Weeks 1–4: 2–2.5 mg, twice weekly
2. Weeks 5+: 2 mg, once weekly

TB-500 is a synthetic peptide based on the active region of thymosin β4, a 43-amino-acid protein that binds G-actin and is involved in cell migration. Thymosin β4 research links it to endothelial and keratinocyte migration, angiogenesis and wound repair.

• In a rat full-thickness wound model, thymosin β4 increased re-epithelialisation by 42% at day 4 and up to 61% at day 7 vs saline.
• Treated wounds contracted at least 11% more by day 7, with more collagen deposition and new blood vessels.
• Keratinocyte migration rose 2–3-fold in cell-culture assays.

• Most evidence is on full-length thymosin β4; data on the TB-500 fragment itself is limited.
• Not approved for human use; listed as prohibited by the World Anti-Doping Agency.

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