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Peptijournal · TB-500 · https://peptijournal.com/compare?c=tb-500 · Impreso
TB-500
Mismo objetivo
01Protocol
- Start
- 2 mg
- Range
- 2–5 mg per week
- Frequency
- 2× weekly (loading), then weekly
- Cycle
- 4–6 week loading, then maintenance
- Vials
- 5 / 10 mg
- Ajuste gradual
- Weeks 1–4: 2–2.5 mg, twice weekly
- Weeks 5+: 2 mg, once weekly
02Quick calculator
03Mechanism of action
TB-500 has been analytically identified as the acetylated thymosin β4 residues 17–23 fragment, Ac-LKKTETQ; some suppliers also use that name for full-length 43-amino-acid thymosin β4. These are not interchangeable. The wound-repair findings below concern full-length thymosin β4, which binds G-actin and participates in cell migration; confirm the sequence of any supplier-labeled product.
04Study endpoints
- In a rat full-thickness wound model, thymosin β4 increased re-epithelialisation by 42% at day 4 and up to 61% at day 7 vs saline.
- In the same full-length thymosin β4 study, treated wounds contracted at least 11% more by day 7, with more collagen deposition and new blood vessels.
- Full-length thymosin β4 increased keratinocyte migration 2–3-fold in cell-culture assays; this is not evidence for an arbitrary TB-500-labeled vial.
05Safety & regulatory findings
- Most evidence is on full-length thymosin β4; data on the TB-500 fragment itself is limited.
- Not approved for human use; listed as prohibited by the World Anti-Doping Agency.
06Citations
3 referencias · ver