Stack Stack · multiple compounds
MOTS-c + 5-Amino-1MQ
Metabolic pairing of a mitochondrial peptide and a small-molecule NNMT inhibitor. Both components have animal data only and the combination has not been studied.
Community opinion
Why people pair them
Called the 'most compelling metabolic stack' in some guides because it targets two pathways (AMPK and NNMT). User reports are polarized and effects described as subtle.
Example discussion (community, not a primary source)Primary sources
What the evidence shows
- MOTS-c: metabolic effects in cells and mice, not human weight-loss data. Source
- 5-Amino-1MQ is a small molecule, not a peptide. NNMT inhibition improved adiposity, insulin sensitivity and fatty-liver measures in obese mice. Source
Caveat: No human safety data for 5-Amino-1MQ; combined liver and metabolic effects are unknown.
What's in it
2 ingredients in separate vials. Tap one to open its own page.
- 01
MOTS-c
Mitochondrial-genome-encoded peptide studied in cell and rodent metabolic models, including insulin sensitivity; these experiments do not establish human exercise-replacement or treatment benefits.
How it works: MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA gene.
Open MOTS-c → - 02
5-Amino-1MQ
NNMT inhibitor
Small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in adipocyte metabolism research.
How it works: 5-Amino-1MQ is a small-molecule (not peptide) inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy metabolism.
Open 5-Amino-1MQ →
No schedule on file
This is a reference-only entry. The site lists its vial sizes and concentrations only — there is no published schedule for it here.
Laboratory reference · catalog presentation
- Research vial sizes
- 10 mg
- Dosing data
- Not listed — reference entry covers vial concentration only.
- Storage
- Follow the specific supplier's documented storage and stability conditions. Temperature, diluent compatibility and shelf life vary by compound and formulation; this catalog does not establish a universal post-mixing expiry.
Reconstitution concentrations
Calculated concentration by volume; 10 units = 0.1 mL on a U-100 syringe. These figures do not verify solubility, BAC-water compatibility, vial capacity or stability.
10 mg vial
1 mL water
10 mg/mL
1 mg / 10 u
2 mL water
5 mg/mL
0.5 mg / 10 u
3 mL water
3.33 mg/mL
0.333 mg / 10 u
| Vial | BAC water | mg/mL | mg per 10 u |
|---|---|---|---|
| 10 mg | 1 mL | 10 | 1 |
| 10 mg | 2 mL | 5 | 0.5 |
| 10 mg | 3 mL | 3.33 | 0.333 |
Notes
Vial size shown is a common MOTS-c listing; 5-Amino-1MQ is often sold as capsules or its own vial.
1
Notes
Vial size shown is a common MOTS-c listing; 5-Amino-1MQ is often sold as capsules or its own vial.
- Vial size shown is a common MOTS-c listing; 5-Amino-1MQ is often sold as capsules or its own vial.
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Research Use Only. Combination entries are laboratory reference data, not instructions for human use.Full disclaimer.