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RESEARCH USE ONLY. Reference data for laboratory research. Not medical advice; not for human consumption.
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Retatrutide + MOTS-c

Community-popular pairing of retatrutide with MOTS-c, supplied as separate vials. No study has tested the combination; MOTS-c metabolic data come from cells and mice.

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Reference only10 mg vialMetabolic / Weight

Community opinion

Why people pair them

Framed online as the main fat-loss driver plus a metabolic 'safety net' for training energy. Sold as named bundles by some vendors.

Example discussion (community, not a primary source)

Primary sources

What the evidence shows

Pair untested; one part lacks human data
  • Retatrutide has randomized human obesity data; MOTS-c was not part of it. Source
  • MOTS-c improved insulin sensitivity and prevented diet-induced obesity in mice. Source
  • A human MOTS-c study is registered (NCT07505745) with no posted results and no retatrutide arm. Source

Caveat: No combination safety data. FDA flags MOTS-c for immunogenicity, impurity and limited human-safety concerns.

What's in it

2 ingredients in separate vials. Tap one to open its own page.

  1. 01

    Retatrutide

    GIP / GLP-1 / glucagon triple agonist

    Investigational triple-hormone receptor agonist evaluated in phase 2/3 obesity trials.

    How it works: Retatrutide (LY3437943) is a single peptide agonist of three receptors: GIP, GLP-1 and glucagon.

    Open Retatrutide →
  2. 02

    MOTS-c

    Mitochondrial-genome-encoded peptide studied in cell and rodent metabolic models, including insulin sensitivity; these experiments do not establish human exercise-replacement or treatment benefits.

    How it works: MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA gene.

    Open MOTS-c →

No schedule on file

This is a reference-only entry. The site lists its vial sizes and concentrations only — there is no published schedule for it here.

Laboratory reference · catalog presentation

Research vial sizes
10 mg
Dosing data
Not listed — reference entry covers vial concentration only.
Storage
Follow the specific supplier's documented storage and stability conditions. Temperature, diluent compatibility and shelf life vary by compound and formulation; this catalog does not establish a universal post-mixing expiry.

Reconstitution concentrations

Calculated concentration by volume; 10 units = 0.1 mL on a U-100 syringe. These figures do not verify solubility, BAC-water compatibility, vial capacity or stability.

10 mg vial

  • 1 mL water

    10 mg/mL

    1 mg / 10 u

  • 2 mL water

    5 mg/mL

    0.5 mg / 10 u

  • 3 mL water

    3.33 mg/mL

    0.333 mg / 10 u

Notes

Vial size shown is a common MOTS-c listing; each compound comes in its own vial.

1
  • Vial size shown is a common MOTS-c listing; each compound comes in its own vial.

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Research Use Only. Combination entries are laboratory reference data, not instructions for human use.Full disclaimer.