RESEARCH USE ONLY. Reference data for laboratory research. Not medical advice; not for human consumption.
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Protocol Single compound

Oxytocin

Endogenous nonapeptide referenced in social-behavior and neuroendocrine research.

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Cognitive

Laboratory reference · in vitro research data

Research vial sizes
2 mg · 5 mg
Dosing data
Not listed — reference entry covers vial concentration only.
Storage
Powder: 2–8 °C, or −20 °C for longer storage. After mixing with BAC water: 2–8 °C, use within about 4 weeks.

Reconstitution concentrations

Concentration per BAC-water volume; 10 units = 0.1 mL on a U-100 syringe.

VialBAC watermg/mLmg per 10 u
2 mg1 mL20.2
2 mg2 mL10.1
2 mg3 mL0.670.067
5 mg1 mL50.5
5 mg2 mL2.50.25
5 mg3 mL1.670.167

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1 mg = 1,000 mcg
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—units

= — mL on a U-100 syringe

Concentration
—
Per unit
—
Doses / vial
—
Syringe
01020304050607080901000.0u
U-100 · 100 units (1 mL)2 unit per line

Research dossier · published literature summary

01

Mechanism of action

Oxytocin is a hypothalamic nonapeptide acting on oxytocin receptors in the uterus, breast and brain. Intranasal oxytocin is studied for social cognition, appetite and stress.

02

Observed research endpoints

  • Meta-analysis (466 participants with neurodevelopmental disorders): no significant effect on emotion recognition and a small significant effect on theory of mind.
  • Meta-analysis of appetite trials: single-dose intranasal oxytocin reduced food intake in non-psychiatric participants but not in anorexia, bulimia, binge-eating disorder or schizophrenia.

03

Regulatory & safety context

  • FDA-approved by injection (e.g. Pitocin) for obstetric uses; intranasal use for behaviour or appetite is not approved.
  • Reviewers call for larger, well-designed randomized trials.

04

Citations

  1. Keech B, et al. Intranasal oxytocin, social cognition and neurodevelopmental disorders: A meta-analysis. Psychoneuroendocrinology. 2018;87:9–19.2018-01Meta-analysisRead paper ↗
  2. Chen CY, et al. Effects of intranasal oxytocin in food intake and craving: A meta-analysis of clinical trials. Clin Nutr. 2021;40:5407–5416.2021-10Meta-analysisRead paper ↗

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